Intravital Microscopy

  • In vivo imaging of various organs in mouse model:
    - Liver, lymph node, spleen, skin, retina, lung, brain, colon, pancreas, small intestine, prostate, kidney, heart, trachea, esophagus, bone marrow, thymus, etc.
  • Image processing & analysis in cellular level:
    - Cell dynamics (cell movement, cell trafficking, cell motility, cell homing)
    - Cell-cell / cell-microenvironment / cell-molecule interaction
    - Cell death / survival, cell distribution, cell differentiation
  • Mouse model of various human disease :
    - Xenograft & syngeneic cancer model using fluorescent cancer cell lines (lung / breast / colon / pancreas cancer, glioblastoma, leukemia, melanoma, etc.)
    - Acute / chronic inflammation model (systemic injection, organ/tissue injury, ischemia-reperfusion injury)
    - Chimera model for intravital imaging of specific cell types (stem cell transplantation, adoptive cell transfer of lymphocyte, etc.)

Live Cell Intravital Imaging

  • In vivo cell dynamics imaging (cell trafficking, cell-cell interaction, cell activity)
  • In vivo time-lapse / mosaic imaging
- Lymph node

- Bone marrow

- Skin

Repetitive Intravital Imaging

  • Long-term repetitive imaging using implanted window chamber
  • Longitudinal cellular-level imaging (pathogenesis visualization)

Wide-area Intravital Imaging

  • In vivo cellular-level mosaic / three-dimensional imaging